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Characterization of CpG island DNA methylation of impairment-related genes in a rat model of cognitive aging

Cognitive abilities, particularly memory formation, vary substantially in the elderly, with some individuals exhibiting dramatic decline with age while others maintain function well into late life. Epigenetic modifications suggest an intriguing mechanism to account for the range of cognitive outcome...

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Detalhes bibliográficos
Main Authors: Haberman, Rebecca P., Quigley, Caitlin K., Gallagher, Michela
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515010/
https://ncbi.nlm.nih.gov/pubmed/22869088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.21291
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