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Characterization of CpG island DNA methylation of impairment-related genes in a rat model of cognitive aging

Cognitive abilities, particularly memory formation, vary substantially in the elderly, with some individuals exhibiting dramatic decline with age while others maintain function well into late life. Epigenetic modifications suggest an intriguing mechanism to account for the range of cognitive outcome...

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Autors principals: Haberman, Rebecca P., Quigley, Caitlin K., Gallagher, Michela
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515010/
https://ncbi.nlm.nih.gov/pubmed/22869088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.21291
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