Treatment Strategies Targeting Excess Hippocampal Activity Benefit Aged Rats with Cognitive Impairment

Excess neural activity in the CA3 region of the hippocampus has been linked to memory impairment in aged rats. We tested whether interventions aimed at reducing this excess activity would improve memory performance. Aged (24 to 28 months old) male Long–Evans rats were characterized in a spatial memo...

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Bibliografiske detaljer
Main Authors: Koh, Ming Teng, Haberman, Rebecca P, Foti, Stacey, McCown, Thomas J, Gallagher, Michela
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820138/
https://ncbi.nlm.nih.gov/pubmed/20032967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.207
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