CRFR1 is expressed on pancreatic β cells, promotes β cell proliferation, and potentiates insulin secretion in a glucose-dependent manner

Corticotropin-releasing factor (CRF), originally characterized as the principal neuroregulator of the hypothalamus-pituitary-adrenal axis, has broad central and peripheral distribution and actions. We demonstrate the presence of CRF receptor type 1 (CRFR1) on primary β cells and show that activation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Huising, Mark O., van der Meulen, Talitha, Vaughan, Joan M., Matsumoto, Masahito, Donaldson, Cynthia J., Park, Hannah, Billestrup, Nils, Vale, Wylie W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818901/
https://ncbi.nlm.nih.gov/pubmed/20080775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913610107
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados