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Urocortin 3 Marks Mature Human Primary and Embryonic Stem Cell-Derived Pancreatic Alpha and Beta Cells

The peptide hormone Urocortin 3 (Ucn 3) is abundantly and exclusively expressed in mouse pancreatic beta cells where it regulates insulin secretion. Here we demonstrate that Ucn 3 first appears at embryonic day (E) 17.5 and, from approximately postnatal day (p) 7 and onwards throughout adult life, b...

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Detalhes bibliográficos
Main Authors: van der Meulen, Talitha, Xie, Ruiyu, Kelly, Olivia G., Vale, Wylie W., Sander, Maike, Huising, Mark O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522648/
https://ncbi.nlm.nih.gov/pubmed/23251699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052181
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