Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets

OBJECTIVE: Complex local crosstalk amongst endocrine cells within the islet ensures tight coordination of their endocrine output. This is illustrated by the recent demonstration that the negative feedback control by delta cells within pancreatic islets determines the homeostatic set-point for plasma...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: DiGruccio, Michael R., Mawla, Alex M., Donaldson, Cynthia J., Noguchi, Glyn M., Vaughan, Joan, Cowing-Zitron, Christopher, van der Meulen, Talitha, Huising, Mark O.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921781/
https://ncbi.nlm.nih.gov/pubmed/27408771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.04.007
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