Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets

OBJECTIVE: Complex local crosstalk amongst endocrine cells within the islet ensures tight coordination of their endocrine output. This is illustrated by the recent demonstration that the negative feedback control by delta cells within pancreatic islets determines the homeostatic set-point for plasma...

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Publicado en:Mol Metab
Autores principales: DiGruccio, Michael R., Mawla, Alex M., Donaldson, Cynthia J., Noguchi, Glyn M., Vaughan, Joan, Cowing-Zitron, Christopher, van der Meulen, Talitha, Huising, Mark O.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921781/
https://ncbi.nlm.nih.gov/pubmed/27408771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.04.007
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