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Glucocorticoids Differentially Regulate the Expression of CRFR1 and CRFR2α in MIN6 Insulinoma Cells and Rodent Islets

Urocortin 3 (Ucn 3), member of the corticotropin-releasing factor (CRF) family of peptide hormones, is released from β-cells to potentiate insulin secretion. Ucn 3 activates the CRF type-2 receptor (CRFR2) but does not activate the type-1 receptor (CRFR1), which was recently demonstrated on β-cells....

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Autors principals: Huising, M. O., Pilbrow, A. P., Matsumoto, M., van der Meulen, T., Park, H., Vaughan, J. M., Lee, S., Vale, W. W.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219054/
https://ncbi.nlm.nih.gov/pubmed/21106875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0791
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