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miR-375 is downregulated by promoter hypermethylation in MIN6 insulinoma cells

Epigenetics may affect the susceptibility for type 2 diabetes mellitus (T2DM). Aberrant DNA methylation patterns are nowadays recognized as a key epigenetic hallmark of T2DM. Previously, our studies have shown that the hypomethylation of human miR-375 promoter may contribute to the pathogenesis of T...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Wei, Yu, Cai, Wei-Juan, Kuang, Xue-Mei, Yin, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963046/
https://ncbi.nlm.nih.gov/pubmed/31949614
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