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COX-2 Dependent Prostacyclin Formation and Blood Pressure Homeostasis: Targeted Exchange of COX Isoforms in Mice
RATIONALE: Cyclooxygenase (COX)-derived prostanoids (PGs) are involved in blood pressure (BP) homeostasis. Both traditional(t) nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit COX-1 and COX-2 and NSAIDs designed to be selective for inhibition of COX-2 cause sodium retention and elevate BP....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818801/ https://ncbi.nlm.nih.gov/pubmed/19940265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.204529 |
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