Selective γ-ketoaldehyde scavengers protect Na(V)1.5 from oxidant-induced inactivation

The cardiac sodium channel (SCN5A, Na(V)1.5) is a key determinant of electrical impulse conduction in cardiac tissue. Acute myocardial infarction leads to diminished sodium channel availability, both because of decreased channel expression and because of greater inactivation of channels already pres...

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Hlavní autoři: Nakajima, T, Davies, SS, Matafonova, E, Potet, F, Amarnath, V, Tallman, KA, Serwa, RA, Porter, NA, Balser, JR, Kupershmidt, S, Roberts, LJ
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818591/
https://ncbi.nlm.nih.gov/pubmed/19962379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.11.016
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