Phosphatidylethanolamines Modified by γ-Ketoaldehyde (γKA) Induce Endoplasmic Reticulum Stress and Endothelial Activation

Peroxidation of plasma lipoproteins has been implicated in the endothelial cell activation and monocyte adhesion that initiate atherosclerosis, but the exact mechanisms underlying this activation remain unclear. Lipid peroxidation generates lipid aldehydes, including the γ-ketoaldehydes (γKA), also...

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Autors principals: Guo, Lilu, Chen, Zhongyi, Cox, Brian E., Amarnath, Venkataraman, Epand, Raquel F., Epand, Richard M., Davies, Sean S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Lipids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093889/
https://ncbi.nlm.nih.gov/pubmed/21454544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.213470
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