Phosphatidylethanolamines Modified by γ-Ketoaldehyde (γKA) Induce Endoplasmic Reticulum Stress and Endothelial Activation

Peroxidation of plasma lipoproteins has been implicated in the endothelial cell activation and monocyte adhesion that initiate atherosclerosis, but the exact mechanisms underlying this activation remain unclear. Lipid peroxidation generates lipid aldehydes, including the γ-ketoaldehydes (γKA), also...

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Autores principales: Guo, Lilu, Chen, Zhongyi, Cox, Brian E., Amarnath, Venkataraman, Epand, Raquel F., Epand, Richard M., Davies, Sean S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Lipids
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093889/
https://ncbi.nlm.nih.gov/pubmed/21454544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.213470
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