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Treatment with a γ-ketoaldehyde scavenger prevents working memory deficits in hApoE4 mice
Both inflammation and oxidative injury are features of Alzheimer’s disease (AD), but the contribution of these intertwined phenomena to the loss of working memory in this disease is unclear. We tested the hypothesis that highly reactive γ-ketoaldehydes that are formed both by non-enzymatic free radi...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289064/ https://ncbi.nlm.nih.gov/pubmed/21709376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-102118 |
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