cJun Modulates Gγ-Globin Gene Expression Via an Upstream cAMP Response Element

The upstream Gγ-globin gene cAMP response element (G-CRE) was previously shown to play a role in drug-mediated fetal hemoglobin induction. This effect is achieved via p38 mitogen activated protein kinase (MAPK)-dependent CREB1 and ATF-2 phosphorylation and G-CRE trans-activation. Since this motif is...

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Bibliografske podrobnosti
Main Authors: Kodeboyina, Sirisha, Balamurugan, Parimaladevi, Liu, Li, Pace, Betty S.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818355/
https://ncbi.nlm.nih.gov/pubmed/19861239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2009.10.002
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