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Regulation of Gγ-Globin Gene by ATF2 and Its Associated Proteins through the cAMP-Response Element

The upstream Gγ-globin cAMP-response element (G-CRE) plays an important role in regulating Gγ-globin expression through binding of ATF2 and its DNA-binding partners defined in this study. ATF2 knockdown resulted in a significant reduction of γ-globin expression accompanied by decreased ATF2 binding...

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Detalhes bibliográficos
Main Authors: Liu, Li, Karmakar, Subhradip, Dhar, Ruby, Mahajan, Milind, Choudhury, Alina, Weissman, Sherman, Pace, Betty S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819381/
https://ncbi.nlm.nih.gov/pubmed/24223142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078253
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