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Dynamics of α-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34(+) cells in culture
OBJECTIVE: The aim of the present study has been to establish serum free culture conditions for the ex vivo expansion and differentiation of human CD34(+) cells into erythroid lineage and to study the chromatin structure, gene expression and transcription factor recruitment at the α–globin locus in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997688/ https://ncbi.nlm.nih.gov/pubmed/19607874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2009.07.001 |
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