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Dynamics of α-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34(+) cells in culture

OBJECTIVE: The aim of the present study has been to establish serum free culture conditions for the ex vivo expansion and differentiation of human CD34(+) cells into erythroid lineage and to study the chromatin structure, gene expression and transcription factor recruitment at the α–globin locus in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mahajan, Milind C, Karmakar, Subhradip, Krause, Diane, Weissman, Sherman M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997688/
https://ncbi.nlm.nih.gov/pubmed/19607874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2009.07.001
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