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Regulation of Gγ-globin gene by ATF2 and its associated proteins through the cAMP-response element.

The upstream Gγ-globin cAMP-response element (G-CRE) plays an important role in regulating Gγ-globin expression through binding of ATF2 and its DNA-binding partners defined in this study. ATF2 knockdown resulted in a significant reduction of γ-globin expression accompanied by decreased ATF2 binding...

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Detalhes bibliográficos
Main Authors: Li Liu, Subhradip Karmakar, Ruby Dhar, Milind Mahajan, Alina Choudhury, Sherman Weissman, Betty S Pace
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3819381?pdf=render
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