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cJun Modulates Gγ-Globin Gene Expression Via an Upstream cAMP Response Element
The upstream Gγ-globin gene cAMP response element (G-CRE) was previously shown to play a role in drug-mediated fetal hemoglobin induction. This effect is achieved via p38 mitogen activated protein kinase (MAPK)-dependent CREB1 and ATF-2 phosphorylation and G-CRE trans-activation. Since this motif is...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818355/ https://ncbi.nlm.nih.gov/pubmed/19861239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2009.10.002 |
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