Selection and Characterization of a DNA Aptamer That Can Discriminate between cJun/cJun and cJun/cFos

The AP-1 family of transcriptional activators plays pivotal roles in regulating a wide range of biological processes from the immune response to tumorigenesis. Determining the roles of specific AP-1 dimers in cells, however, has remained challenging because common molecular biology techniques are un...

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Bibliographic Details
Main Authors: Walters, Ryan D., McSwiggen, David T., Goodrich, James A., Kugel, Jennifer F.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072727/
https://ncbi.nlm.nih.gov/pubmed/24968026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101015
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