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Role of Stat3 and GATA-1 Interactions in γ-Globin Gene Expression
OBJECTIVE: We previously demonstrated a silencing role for Stat3 in γ-globin gene regulation in primary erythroid cells. Recently GATA-1, a key transcription factor involved in hematopoietic cell development was shown to directly inhibit the activity of Stat3 in vivo. Therefore we completed studies...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746970/ https://ncbi.nlm.nih.gov/pubmed/19447160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2009.05.004 |
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