Role of Stat3 and GATA-1 Interactions in γ-Globin Gene Expression

OBJECTIVE: We previously demonstrated a silencing role for Stat3 in γ-globin gene regulation in primary erythroid cells. Recently GATA-1, a key transcription factor involved in hematopoietic cell development was shown to directly inhibit the activity of Stat3 in vivo. Therefore we completed studies...

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Hlavní autoři: Yao, Xiao, Kodeboyina, Sirisha, Liu, Li, Dzandu, James, Sangerman, Jose, Ofori-Acquah, Solomon F., Pace, Betty S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746970/
https://ncbi.nlm.nih.gov/pubmed/19447160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2009.05.004
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