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Sustained enhancement of OCTN1 transporter expression in association with hydroxyurea induced gamma-globin expression in erythroid progenitors

The clinical benefits of hydroxyurea treatment in patients with sickle cell disease (SCD) are due largely to increased gamma-globin expression. However, mechanisms that control gamma-globin expression by hydroxyurea in erythroid progenitors are incompletely understood. Here, we investigated the role...

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Bibliografiske detaljer
Udgivet i:Exp Hematol
Main Authors: Walker, Aisha L., Ofori-Acquah, Solomon
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5164842/
https://ncbi.nlm.nih.gov/pubmed/27616638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.09.001
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