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Erythroid DAMPs drive inflammation in SCD
In this issue of Blood, Chen et al show that heme is released during erythrocyte hemolysis in sickle cell disease, activating the innate immune response and triggering the release of neutrophil extracellular traps (NETs) to promote lung injury.(1)
Shranjeno v:
| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Hematology
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055918/ https://ncbi.nlm.nih.gov/pubmed/24926069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-03-563874 |
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