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Erythroid DAMPs drive inflammation in SCD

In this issue of Blood, Chen et al show that heme is released during erythrocyte hemolysis in sickle cell disease, activating the innate immune response and triggering the release of neutrophil extracellular traps (NETs) to promote lung injury.(1)

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Podrobná bibliografie
Hlavní autoři: Gladwin, Mark T., Ofori-Acquah, Solomon F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055918/
https://ncbi.nlm.nih.gov/pubmed/24926069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-03-563874
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