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Sustained enhancement of OCTN1 transporter expression in association with hydroxyurea induced gamma-globin expression in erythroid progenitors

The clinical benefits of hydroxyurea treatment in patients with sickle cell disease (SCD) are due largely to increased gamma-globin expression. However, mechanisms that control gamma-globin expression by hydroxyurea in erythroid progenitors are incompletely understood. Here, we investigated the role...

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Detaylı Bibliyografya
Yayımlandı:Exp Hematol
Asıl Yazarlar: Walker, Aisha L., Ofori-Acquah, Solomon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5164842/
https://ncbi.nlm.nih.gov/pubmed/27616638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.09.001
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