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Histone Deacetylase 9 Activates γ-Globin Gene Expression in Primary Erythroid Cells
Strategies to induce fetal hemoglobin (HbF) synthesis for the treatment of β-hemoglobinopathies probably involve protein modifications by histone deacetylases (HDACs) that mediate γ-globin gene regulation. However, the role of individual HDACs in globin gene expression is not very well understood; t...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023528/ https://ncbi.nlm.nih.gov/pubmed/21078662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115725 |
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