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Histone Deacetylase 9 Activates γ-Globin Gene Expression in Primary Erythroid Cells

Strategies to induce fetal hemoglobin (HbF) synthesis for the treatment of β-hemoglobinopathies probably involve protein modifications by histone deacetylases (HDACs) that mediate γ-globin gene regulation. However, the role of individual HDACs in globin gene expression is not very well understood; t...

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Bibliografiset tiedot
Päätekijät: Muralidhar, Shalini A., Ramakrishnan, Valya, Kalra, Inderdeep S., Li, Wei, Pace, Betty S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023528/
https://ncbi.nlm.nih.gov/pubmed/21078662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115725
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