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REGULATION OF γ-GLOBIN GENE EXPRESSION INVOLVES SIGNALING THROUGH THE p38 MAPK/CREB1 PATHWAY

In response to sodium butyrate and trichostatin A treatment in erythroid cells, p38 mitogen activated protein kinase (MAPK) mediates fetal hemoglobin induction by activating cAMP response element binding protein 1 (CREB1). To expand on this observation, we completed studies to determine the role of...

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Detalhes bibliográficos
Main Authors: Ramakrishnan, Valya, Pace, Betty S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695476/
https://ncbi.nlm.nih.gov/pubmed/21497119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2011.03.003
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