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IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway()

Autophagy is a major innate immune defense pathway in both plants and animals. In mammals, this cascade can be elicited by cytokines (IFN-γ) or pattern recognition receptors (TLRs and nucleotide-binding oligomerization domain-like receptors [NLRs]). Many signaling components in TLR- and NLR-induced...

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Detalhes bibliográficos
Main Authors: Matsuzawa, Takeshi, Kim, Bae-Hoon, Shenoy, Avinash R., Kamitani, Shigeki, Miyake, Masami, MacMicking, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392356/
https://ncbi.nlm.nih.gov/pubmed/22675202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102041
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