Breadth of Human Immunodeficiency Virus-Specific Neutralizing Activity in Sera: Clustering Analysis and Association with Clinical Variables

Induction of antibodies that neutralize a broad range of human immunodeficiency virus type 1 (HIV-1) isolates is a major goal of vaccine development. To study natural examples of broad neutralization, we analyzed sera from 103 HIV-1-infected subjects. Among progressor patients, 20% of sera neutraliz...

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Hauptverfasser: Doria-Rose, Nicole A., Klein, Rachel M., Daniels, Marcus G., O'Dell, Sijy, Nason, Martha, Lapedes, Alan, Bhattacharya, Tanmoy, Migueles, Stephen A., Wyatt, Richard T., Korber, Bette T., Mascola, John R., Connors, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812355/
https://ncbi.nlm.nih.gov/pubmed/19923174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01482-09
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