Breadth of Human Immunodeficiency Virus-Specific Neutralizing Activity in Sera: Clustering Analysis and Association with Clinical Variables

Induction of antibodies that neutralize a broad range of human immunodeficiency virus type 1 (HIV-1) isolates is a major goal of vaccine development. To study natural examples of broad neutralization, we analyzed sera from 103 HIV-1-infected subjects. Among progressor patients, 20% of sera neutraliz...

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Detalhes bibliográficos
Main Authors: Doria-Rose, Nicole A., Klein, Rachel M., Daniels, Marcus G., O'Dell, Sijy, Nason, Martha, Lapedes, Alan, Bhattacharya, Tanmoy, Migueles, Stephen A., Wyatt, Richard T., Korber, Bette T., Mascola, John R., Connors, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812355/
https://ncbi.nlm.nih.gov/pubmed/19923174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01482-09
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