Breadth of Human Immunodeficiency Virus-Specific Neutralizing Activity in Sera: Clustering Analysis and Association with Clinical Variables

Induction of antibodies that neutralize a broad range of human immunodeficiency virus type 1 (HIV-1) isolates is a major goal of vaccine development. To study natural examples of broad neutralization, we analyzed sera from 103 HIV-1-infected subjects. Among progressor patients, 20% of sera neutraliz...

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Autores principales: Doria-Rose, Nicole A., Klein, Rachel M., Daniels, Marcus G., O'Dell, Sijy, Nason, Martha, Lapedes, Alan, Bhattacharya, Tanmoy, Migueles, Stephen A., Wyatt, Richard T., Korber, Bette T., Mascola, John R., Connors, Mark
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812355/
https://ncbi.nlm.nih.gov/pubmed/19923174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01482-09
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