Frequency and Phenotype of Human Immunodeficiency Virus Envelope-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies

Induction of broadly cross-reactive neutralizing antibodies (NAb) is an important goal for a prophylactic human immunodeficiency virus type 1 (HIV-1) vaccine. Some HIV-infected patients make a NAb response that reacts with diverse strains of HIV-1, but most candidate vaccines have induced NAb only a...

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Detalhes bibliográficos
Main Authors: Doria-Rose, Nicole A., Klein, Rachel M., Manion, Maura M., O'Dell, Sijy, Phogat, Adhuna, Chakrabarti, Bimal, Hallahan, Claire W., Migueles, Stephen A., Wrammert, Jens, Ahmed, Rafi, Nason, Martha, Wyatt, Richard T., Mascola, John R., Connors, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612342/
https://ncbi.nlm.nih.gov/pubmed/18922865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01583-08
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