Frequency and Phenotype of Human Immunodeficiency Virus Envelope-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies

Induction of broadly cross-reactive neutralizing antibodies (NAb) is an important goal for a prophylactic human immunodeficiency virus type 1 (HIV-1) vaccine. Some HIV-infected patients make a NAb response that reacts with diverse strains of HIV-1, but most candidate vaccines have induced NAb only a...

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Dades bibliogràfiques
Autors principals: Doria-Rose, Nicole A., Klein, Rachel M., Manion, Maura M., O'Dell, Sijy, Phogat, Adhuna, Chakrabarti, Bimal, Hallahan, Claire W., Migueles, Stephen A., Wrammert, Jens, Ahmed, Rafi, Nason, Martha, Wyatt, Richard T., Mascola, John R., Connors, Mark
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612342/
https://ncbi.nlm.nih.gov/pubmed/18922865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01583-08
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