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Broad HIV-1 neutralization mediated by CD4-binding site antibodies
We have identified several patient sera showing potent and broad HIV-1 neutralization. Using antibody adsorption and elution from selected gp120 variants, the neutralizing specificities of the two most broadly reactive sera were mapped to the primary receptor CD4–binding region of HIV-1 gp120. Novel...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584972/ https://ncbi.nlm.nih.gov/pubmed/17721546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1624 |
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