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Mechanism of Neutralization by the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01
The structure of VRC01 in complex with the HIV-1 gp120 core reveals that this broadly neutralizing CD4 binding site (CD4bs) antibody partially mimics the interaction of the primary virus receptor, CD4, with gp120. Here, we extended the investigation of the VRC01-gp120 core interaction to the biologi...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3165784/ https://ncbi.nlm.nih.gov/pubmed/21715490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00754-11 |
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