Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

During natural infection by HIV-1, antibodies are generated against the region of the viral gp120 envelope glycoprotein that binds CD4, the primary receptor for HIV-1. Among these antibodies, VRC01 achieves extensive neutralization of diverse viral strains. To understand the structural basis for its...

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Bibliografski detalji
Glavni autori: Zhou, Tongqing, Georgiev, Ivelin, Wu, Xueling, Yang, Zhi-Yong, Dai, Kaifan, Finzi, Andrés, Kwon, Young Do, Scheid, Johannes, Shi, Wei, Xu, Ling, Yang, Yongping, Zhu, Jiang, Nussenzweig, Michel C., Sodroski, Joseph, Shapiro, Lawrence, Nabel, Gary J., Mascola, John R., Kwong, Peter D.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981354/
https://ncbi.nlm.nih.gov/pubmed/20616231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1192819
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