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De novo identification of VRC01 class HIV-1–neutralizing antibodies by next-generation sequencing of B-cell transcripts

Next-generation sequencing of antibody transcripts provides a wealth of data, but the ability to identify function-specific antibodies solely on the basis of sequence has remained elusive. We previously characterized the VRC01 class of antibodies, which target the CD4-binding site on gp120, appear i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zhu, Jiang, Wu, Xueling, Zhang, Baoshan, McKee, Krisha, O’Dell, Sijy, Soto, Cinque, Zhou, Tongqing, Casazza, Joseph P., Mullikin, James C., Kwong, Peter D., Mascola, John R., Shapiro, Lawrence
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808619/
https://ncbi.nlm.nih.gov/pubmed/24106303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306262110
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