Frequency and Phenotype of Human Immunodeficiency Virus Envelope-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies

Induction of broadly cross-reactive neutralizing antibodies (NAb) is an important goal for a prophylactic human immunodeficiency virus type 1 (HIV-1) vaccine. Some HIV-infected patients make a NAb response that reacts with diverse strains of HIV-1, but most candidate vaccines have induced NAb only a...

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Détails bibliographiques
Auteurs principaux: Doria-Rose, Nicole A., Klein, Rachel M., Manion, Maura M., O'Dell, Sijy, Phogat, Adhuna, Chakrabarti, Bimal, Hallahan, Claire W., Migueles, Stephen A., Wrammert, Jens, Ahmed, Rafi, Nason, Martha, Wyatt, Richard T., Mascola, John R., Connors, Mark
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612342/
https://ncbi.nlm.nih.gov/pubmed/18922865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01583-08
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