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Discovery and Binding Studies on a Series of Novel Pin1 Ligands
Pin1 plays a key role in various biological cellular processes via the recognition of phosphorylated Ser/Thr-Proline motifs. Moreover, high expression levels of Pin1 are correlated to tumorgenesis in some cancer types. Here, we identify a novel series of small molecular weight compounds with a core...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810120/ https://ncbi.nlm.nih.gov/pubmed/19291099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2009.00795.x |
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