Structure Activity Relationship Studies of a Novel Series of Anthrax Lethal Factor Inhibitors

We report on the identification of a novel small molecule inhibitor of anthrax lethal factor using a high-throughput screening approach. Guided by molecular docking studies, we carried out structure activity relationship (SAR) studies and evaluated activity and selectivity of most promising compound...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Johnson, Sherida L., Chen, Li-Hsing, Barille, Elisa, Emdadi, Aras, Sabet, Mojgan, Yuan, Hongbin, Wei, Jun, Guiney, Donald, Pellecchia, Maurizio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730741/
https://ncbi.nlm.nih.gov/pubmed/19359184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.03.040
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky