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Structure Activity Relationship Studies of a Novel Series of Anthrax Lethal Factor Inhibitors
We report on the identification of a novel small molecule inhibitor of anthrax lethal factor using a high-throughput screening approach. Guided by molecular docking studies, we carried out structure activity relationship (SAR) studies and evaluated activity and selectivity of most promising compound...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730741/ https://ncbi.nlm.nih.gov/pubmed/19359184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.03.040 |
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