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Efficient synthetic inhibitors of anthrax lethal factor

Inhalation anthrax is a deadly disease for which there is currently no effective treatment. Bacillus anthracis lethal factor (LF) metalloproteinase is an integral component of the tripartite anthrax lethal toxin that is essential for the onset and progression of anthrax. We report here on a fragment...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Forino, Martino, Johnson, Sherida, Wong, Thiang Y., Rozanov, Dmitri V., Savinov, Alexei Y., Li, Wei, Fattorusso, Roberto, Becattini, Barbara, Orry, Andrew J., Jung, Dawoon, Abagyan, Ruben A., Smith, Jeffrey W., Alibek, Ken, Liddington, Robert C., Strongin, Alex Y., Pellecchia, Maurizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1160517/
https://ncbi.nlm.nih.gov/pubmed/15983377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502733102
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