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Identification of a Novel Mcl-1 Protein Binding Motif

Recent characterization of Mcl-1 as the primary anti-apoptotic Bcl-2 family member expressed in solid tumors, coupled with its ability to enable therapeutic resistance, has provided the impetus for further study into how Mcl-1 is involved in apoptosis signaling. Here, we employ Sabutoclax, a potent...

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Detalles Bibliográficos
Main Authors: Placzek, William J., Sturlese, Mattia, Wu, Bainan, Cellitti, Jason F., Wei, Jun, Pellecchia, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220561/
https://ncbi.nlm.nih.gov/pubmed/21953453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.305326
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