Novel effects mediated by bradykinin and pharmacological characterization of bradykinin B(2) receptor antagonism in human synovial fibroblasts

BACKGROUND AND PURPOSE: Bradykinin (BK) and B(2) receptors have been implicated in the pathophysiology of osteoarthritis (OA), and synovitis is one of its hallmarks. Here, the selective B(2) receptor antagonists MEN16132 and icatibant have been pharmacologically characterized in human synovial cells...

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Bibliografski detalji
Glavni autori: Bellucci, F, Cucchi, P, Catalani, C, Giuliani, S, Meini, S, Maggi, CA
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2009
Teme:
Research Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807661/
https://ncbi.nlm.nih.gov/pubmed/20050188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00511.x
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