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Comparative antagonist pharmacology at the native mouse bradykinin B(2) receptor: radioligand binding and smooth muscle contractility studies
BACKGROUND AND PURPOSE: The aim was to characterize the recently discovered non-peptide antagonist MEN16132 at the mouse B(2) receptor, relative to other antagonists. EXPERIMENTAL APPROACH: [(3)H]-BK binding experiments used mouse lung and ileum tissue membranes and antagonist potency was measured i...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2013903/ https://ncbi.nlm.nih.gov/pubmed/17179941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706995 |
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