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Bradykinin and B(2) receptor antagonism in rat and human articular chondrocytes

BACKGROUND AND PURPOSE: In osteoarthritis (OA), bradykinin (BK) is known to contribute to pain and synovitis, but not to cartilage degradation. Here, we investigated effects of BK and its antagonists on chondrocytes, cells involved in cartilage homeostasis. EXPERIMENTAL APPROACH: BK receptor density...

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Main Authors: Meini, S, Cucchi, P, Catalani, C, Bellucci, F, Giuliani, S, Maggi, CA
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041251/
https://ncbi.nlm.nih.gov/pubmed/20946124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01062.x
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