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A different molecular interaction of bradykinin and the synthetic agonist FR190997 with the human B(2) receptor: evidence from mutational analysis
1. Binding affinity at the [(3)H]-BK binding site and activity as inositol phosphate (IP) production by the peptide bradykinin (BK) and the nonpeptide FR190997 were studied at wild-type or point-mutated human B(2) receptors (hB(2)R) expressed in CHO cells. 2. The effect of the following mutations we...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574048/ https://ncbi.nlm.nih.gov/pubmed/12970081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705454 |
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