Phosphorylation of Synucleins by Members of the Polo-like Kinase Family

Phosphorylation of α-synuclein (α-syn) at Ser-129 is a hallmark of Parkinson disease and related synucleinopathies. However, the identity of the natural kinases and phosphatases responsible for regulating α-syn phosphorylation remain unknown. Here we demonstrate that three closely related members of...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Mbefo, Martial K., Paleologou, Katerina E., Boucharaba, Ahmed, Oueslati, Abid, Schell, Heinrich, Fournier, Margot, Olschewski, Diana, Yin, Guowei, Zweckstetter, Markus, Masliah, Eliezer, Kahle, Philipp J., Hirling, Harald, Lashuel, Hilal A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Protein Synthesis, Post-Translational Modification, and Degradation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807335/
https://ncbi.nlm.nih.gov/pubmed/19889641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.081950
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi