טוען...
Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation
During somatic hypermutation (SHM), B cells introduce mutations into their immunoglobulin genes to generate high affinity antibodies. Current models suggest a separation in the generation of G/C transversions by the Ung2-dependent pathway and the generation of A/T mutations by the Msh2/ubiquitinated...
שמור ב:
| Main Authors: | , , , |
|---|---|
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Rockefeller University Press
2009
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806606/ https://ncbi.nlm.nih.gov/pubmed/19901081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091707 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|