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PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
Both the programmed death (PD) 1–PD-ligand (PD-L) pathway and regulatory T (T reg) cells are instrumental to the maintenance of peripheral tolerance. We demonstrate that PD-L1 has a pivotal role in regulating induced T reg (iT reg) cell development and sustaining iT reg cell function. PD-L1(−/−) ant...
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| Главные авторы: | , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806460/ https://ncbi.nlm.nih.gov/pubmed/20008522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090847 |
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