Llwytho...

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

Both the programmed death (PD) 1–PD-ligand (PD-L) pathway and regulatory T (T reg) cells are instrumental to the maintenance of peripheral tolerance. We demonstrate that PD-L1 has a pivotal role in regulating induced T reg (iT reg) cell development and sustaining iT reg cell function. PD-L1(−/−) ant...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Francisco, Loise M., Salinas, Victor H., Brown, Keturah E., Vanguri, Vijay K., Freeman, Gordon J., Kuchroo, Vijay K., Sharpe, Arlene H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806460/
https://ncbi.nlm.nih.gov/pubmed/20008522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090847
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