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The effects of sitaxentan on sildenafil pharmacokinetics and pharmacodynamics in healthy subjects
AIMS: This study evaluated the effects of sitaxentan on the pharmacodynamic [systemic blood pressure (BP)] and pharmacokinetic (PK) parameters of sildenafil in healthy volunteers. METHODS: Healthy subjects (18–60 years, n= 24) were randomized into two sequence groups. Group 1 received sitaxentan sod...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805874/ https://ncbi.nlm.nih.gov/pubmed/20078609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03541.x |
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